1. Taylor OG, Brzozowski JS, Skelding KA. Glioblastoma multiforme: an overview of emerging therapeutic targets. Front Oncol. 2019;9:963. [
DOI:10.3389/fonc.2019.00963] [
PMID] [
PMCID]
2. Chen B, Chen C, Zhang Y, Xu J. Recent incidence trend of elderly patients with glioblastoma in the United States, 2000-2017. BMC cancer. 2021;21(1):1-10. [
DOI:10.1186/s12885-021-09033-7] [
PMID] [
PMCID]
3. Lukas RV, Wainwright DA, Ladomersky E, Sachdev S, Sonabend AM, Stupp R. Newly diagnosed glioblastoma: a review on clinical management. Oncology (Williston Park). 2019;33(3):91-100.
4. Tan AC, Ashley DM, López GY, Malinzak M, Friedman HS, Khasraw M. Management of glioblastoma: State of the art and future directions. CA Cancer J Clin. 2020;70(4):299-312. [
DOI:10.3322/caac.21613] [
PMID]
5. Iwamoto FM, Fine HA. Bevacizumab for malignant gliomas. Arch Neurol. 2010;67(3):285-288. [
DOI:10.1001/archneurol.2010.11] [
PMID] [
PMCID]
6. Tamimi AF, Juweid M, Vleeschouwer SD. Epidemiology and outcome of glioblastoma. Exon Publications. 2017:143-53. [
DOI:10.15586/codon.glioblastoma.2017.ch8] [
PMID]
7. Sanz MA, Fenaux P, Tallman MS, Estey EH, Löwenberg B, Naoe T, et al. Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet. Blood. 2019;133(15):1630-1643. [
DOI:10.1182/blood-2019-01-894980] [
PMID] [
PMCID]
8. Leung LL, Lam SK, Li YY, Ho JCM. Tumour growth‑suppressive effect of arsenic trioxide in squamous cell lung carcinoma. Oncol Lett. 2017;14(3):3748-3754. [
DOI:10.3892/ol.2017.6646] [
PMID] [
PMCID]
9. Zhang T, Wang S, Hong L, Wang X, Qi Q. Arsenic trioxide induces apoptosis of rat hepatocellular carcinoma cells in vivo. J Exp Clin Cancer Res. 2003;22(1):61-8.
10. Fang Y, Zhang Z. Arsenic trioxide as a novel anti-glioma drug: a review. Cell Mol Biol Lett. 2020;25:44. [
DOI:10.1186/s11658-020-00236-7] [
PMID] [
PMCID]
11. Cheng Y, Li Y, Ma C, Song Y, Xu H, Yu H, et al. Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction. Oncotarget. 2016;7(11):12682-92. [
DOI:10.18632/oncotarget.7259] [
PMID] [
PMCID]
12. Osuka S, Van Meir EG. Overcoming therapeutic resistance in glioblastoma: the way forward. J Clin Invest. 2017;127(2):415-426. [
DOI:10.1172/JCI89587] [
PMID] [
PMCID]
13. Cahill KE, Morshed RA, Yamini B. Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy. Neuro Oncol. 2015;18(3):329-39. [
DOI:10.1093/neuonc/nov265] [
PMID] [
PMCID]
14. Puliyappadamba VT, Hatanpaa KJ, Chakraborty S, Habib AA. The role of NF-κB in the pathogenesis of glioma. Mol Cell Oncol. 2014;1(3):e963478. [
DOI:10.4161/23723548.2014.963478] [
PMID] [
PMCID]
15. Soubannier V, Stifani S. NF-κB signalling in glioblastoma. Biomedicines. 2017;5(2):29. [
DOI:10.3390/biomedicines5020029] [
PMID] [
PMCID]
16. Avci NG, Ebrahimzadeh-Pustchi S, Akay YM, Esquenazi Y, Tandon N, Zhu J-J, et al. NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB (p65) and actin cytoskeleton regulatory pathways. Scientific Reports. 2020;10(1):1-14. [
DOI:10.1038/s41598-020-70392-5] [
PMID] [
PMCID]
17. Zanotto-Filho A, Braganhol E, Schröder R, de Souza LHT, Dalmolin RJ, Pasquali MAB, et al. NFκB inhibitors induce cell death in glioblastomas. Biochem Pharmacol. 2011;81(3):412-24. [
DOI:10.1016/j.bcp.2010.10.014] [
PMID]
18. Krishnan N, Bencze G, Cohen P, Tonks NK. The anti‐inflammatory compound BAY‐11‐7082 is a potent inhibitor of protein tyrosine phosphatases. FEBS J. 2013;280(12):2830-2841. [
DOI:10.1111/febs.12283] [
PMID] [
PMCID]
19. Momeny M, Yousefi H, Eyvani H, Moghaddaskho F, Salehi A, Esmaeili F, et al. Blockade of nuclear factor-κB (NF-κB) pathway inhibits growth and induces apoptosis in chemoresistant ovarian carcinoma cells. Int J Biochem Cell Biol. 2018;99:1-9. [
DOI:10.1016/j.biocel.2018.03.015] [
PMID]
20. Chou T-C. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010;70(2):440-6. [
DOI:10.1158/0008-5472.CAN-09-1947] [
PMID]
21. Baakhlagh S, Kashani B, Zandi Z, Bashash D, Moradkhani M, Nasrollahzadeh A, et al. Toll-like receptor 4 signaling pathway is correlated with pathophysiological characteristics of AML patients and its inhibition using TAK-242 suppresses AML cell proliferation. Int Immunopharmacol. 2020;90:107202. [
DOI:10.1016/j.intimp.2020.107202] [
PMID]
22. Xia Y, Shen S, Verma IM. NF-κB, an active player in human cancers. Cancer Immunol Res. 2014;2(9):823-30. [
DOI:10.1158/2326-6066.CIR-14-0112] [
PMID] [
PMCID]
23. Basseres D, Baldwin A. Nuclear factor-κ B and inhibitor of κ B kinase pathways in oncogenic initiation and progression. Oncogene. 2006;25(51):6817-30. [
DOI:10.1038/sj.onc.1209942] [
PMID]
24. Nasrollahzadeh A, Bashash D, Kabuli M, Zandi Z, Kashani B, Zaghal A, et al. Arsenic trioxide and BIBR1532 synergistically inhibit breast cancer cell proliferation through attenuation of NF-κB signaling pathway. Life Sci. 2020;257:118060. [
DOI:10.1016/j.lfs.2020.118060] [
PMID]
25. Mesbahi Y, Zekri A, Ahmadian S, Alimoghaddam K, Ghavamzadeh A, Ghaffari SH. Targeting of EGFR increase anti-cancer effects of arsenic trioxide: Promising treatment for glioblastoma multiform. Eur J Pharmacol. 2018;820:274-285. [
DOI:10.1016/j.ejphar.2017.12.041] [
PMID]
26. Vollmann-Zwerenz A, Leidgens V, Feliciello G, Klein CA, Hau P. Tumor cell invasion in glioblastoma. Int J Mol Sci. 2020;21(6):1932. [
DOI:10.3390/ijms21061932] [
PMID] [
PMCID]
27. Lee DW, Ramakrishnan D, Valenta J, Parney IF, Bayless KJ, Sitcheran R. The NF-κB RelB protein is an oncogenic driver of mesenchymal glioma. PloS one. 2013;8(2):e57489. [
DOI:10.1371/journal.pone.0057489] [
PMID] [
PMCID]
28. EliasM C, TozerK R. TWIST is Expressed in Human Gliomas and Promotes Invasion. Neoplasia. 2005;7(9):824-837. [
DOI:10.1593/neo.04352] [
PMID] [
PMCID]
29. Yu C-F, Chen F-H, Lu M-H, Hong J-H, Chiang C-S. Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion. Br J Cancer. 2017;117(12):1828-1836. [
DOI:10.1038/bjc.2017.362] [
PMID] [
PMCID]
30. Piao Y, Henry V, Tiao N, Park SY, Martinez-Ledesma J, Dong JW, et al. Targeting intercellular adhesion molecule-1 prolongs survival in mice bearing bevacizumab-resistant glioblastoma. Oncotarget. 2017;8(57):96970-96983. [
DOI:10.18632/oncotarget.18859] [
PMID] [
PMCID]
31. Demchik LL, Sameni M, Nelson K, Mikkelsen T, Sloane BF. Cathepsin B and glioma invasion. Int J Dev Neurosci. 1999;17(5-6):483-94. [
DOI:10.1016/S0736-5748(99)00011-8]
32. Valdés-Rives SA, Casique-Aguirre D, Germán-Castelán L, Velasco-Velázquez MA, González-Arenas A. Apoptotic signaling pathways in glioblastoma and therapeutic implications. Biomed Res Int. 2017;2017:7403747. [
DOI:10.1155/2017/7403747] [
PMID] [
PMCID]
33. Steinbach JP, Weller M. Apoptosis in gliomas: molecular mechanisms and therapeutic implications. J Neurooncol. 2004;70(2):245-54. [
DOI:10.1007/s11060-004-2753-4]
34. Qiu B, Wang Y, Tao J, Wang Y. Expression and correlation of Bcl-2 with pathological grades in human glioma stem cells. Oncol Rep. 2012;28(1):155-60.
35. Emery IF, Gopalan A, Wood S, Chow K-h, Battelli C, George J, et al. Expression and function of ABCG2 and XIAP in glioblastomas. J Neurooncol. 2017;133(1):47-57. [
DOI:10.1007/s11060-017-2422-z] [
PMID] [
PMCID]
36. Vellanki SHK, Grabrucker A, Liebau S, Proepper C, Eramo A, Braun V, et al. Small-molecule XIAP inhibitors enhance γ-irradiation-induced apoptosis in glioblastoma. Neoplasia. 2009;11(8):743-52. [
DOI:10.1593/neo.09436] [
PMID] [
PMCID]
37. Tong X, Yang P, Wang K, Liu Y, Liu X, Shan X, et al. Survivin is a prognostic indicator in glioblastoma and may be a target of microRNA‑218. Oncol Lett. 2019;18(1):359-367. [
DOI:10.3892/ol.2019.10335] [
PMID] [
PMCID]