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'); Reports of Biochemistry and Molecular Biology rbmb.net Basic Sciences http://rbmb.net 1 admin 2322-3480 2322-3480 10.61882/rbmb en jalali 1398 4 1 gregorian 2019 7 1 8 2 online 1 fulltext
en The Effect of Low Testosterone and Estrogen Levels on Progressive Coronary Artery Disease in Men زیست شناسی ملکولی Molecular Biology مقالات اصلی Original Article <div style="text-align: justify;"><strong><em>Background:</em></strong><strong><em> &nbsp;</em></strong>Age-related morbidity and mortality rates from coronary heart disease (CHD) are higher in men than in women. Abnormal androgen levels cause a variety of abnormal symptoms in men. Testosterone and estrogen are the main sex hormone in men and women, respectively, and studies have shown that they have important roles in cardiovascular health and disease.<br> <strong><em>Methods:</em></strong> We measured testosterone and estrogen in 102 men with coronary heart disease and 45 controls. Blood samples were collected from subjects and plasma testosterone and estrogen were measured by ELISA.<br> <strong><em>Results:</em></strong> &nbsp;Men with coronary heart disease had less testosterone (OD Ratio: 0.782) and estrogen (OD Ratio: 0.955) than controls.<br> <strong><em>Conclusions:</em></strong> Low testosterone and estrogen levels correlate with coronary artery disease.</div> Coronary artery disease, Estrogen, Testosterone. 168 171 http://rbmb.net/browse.php?a_code=A-10-95-4&slc_lang=en&sid=1 Mansoureh Bajelan bajelan@yahoo.com 100319475328460017272 100319475328460017272 No Cellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran. Negar Etehad Roodi negar.etehad@yahoo.com 100319475328460017273 100319475328460017273 No Cellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran. & Cardiovascular Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Mahdy Hasanzadeh Daloee hasanzadeh@yahoo.com 100319475328460017274 100319475328460017274 No Department of Tissue Engineering & Regenerative Medicine, Iran University of Medical Science, Tehran, Iran. Mansoureh Farhangnia farhangnia@yahoo.com 100319475328460017275 100319475328460017275 No Cardiovascular Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Ali Samadi Kuchaksaraei samadikuchaksaraee@yahoo.com 100319475328460017276 100319475328460017276 Yes Cellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran. & Cardiovascular Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.