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'); Reports of Biochemistry and Molecular Biology rbmb.net Basic Sciences http://rbmb.net 1 admin 2322-3480 2322-3480 10.61882/rbmb en jalali 1398 10 1 gregorian 2020 1 1 8 4 online 1 fulltext
en Investigation of the Effects of Apple Trees Infection by Erwinia amylovora on the Expression of Pathogenesis-Related Proteins Homologous to Allergens ایمنی شناسی Immunology مقالات اصلی Original Article <div style="text-align: justify;"><strong><em>Background:</em></strong> Pathogenesis-related (PR) proteins are induced in response to biotic and abiotic stresses. Some plant proteins, including Mal d 1, Mal d 2, and Mal d 3 in apple, are allergens. In this study, the effects of <em>Erwinia amylovora</em>&nbsp;infection of two apple cultivars, Red and Golden Delicious, on the expression of PR proteins&nbsp;homologous&nbsp;to Mal d 1, 2, and 3 were investigated.<br> <br> <strong><em>Methods:</em></strong> In natural conditions trees with or without disease symptoms were sampled. In addition, seeds of the cultivars were grown in a greenhouse and seedlings were examined in three groups: 1) those inoculated by&nbsp;<em>E. amylovora</em>, 2) those inoculated by sterilized distilled water, and 3) uninoculated. Real-time PCR was used to determine expression of the Mal d 1, 2, and 3 genes (<em>Mal d 1, 2, </em>and <em>3</em>) in infected and uninfected samples. Statistical analyses were performed using SPSS and graphs were produced by Excel. P values < 0.05 were considered significant.<br> <br> <strong><em>Results:</em></strong> &nbsp;The analysis of variance showed that in natural conditions the effect of infection on the mean relative expression of <em>Mal d 2 </em>and<em> 3</em> was significant, and more so in Red than in Golden Delicious. The analysis of variance of the greenhouse samples showed that the effect of infection on the mean relative expression of <em>Mal d 1, 2, </em>and<em> 3</em> in both cultivars was significant.<br> <br> <strong><em>Conclusions:</em></strong>Our results suggest that Mal d 2 is more related to plant defense than Mal d 1 or Mal d 3, and is more highly expressed in<em> E. amylovora</em>-resistant than in <em>E. amylovora</em>-sensitive cultivars.</div> Allergens, Erwinia amylovora, Homologous, Pathogenesis-related proteins. 376 382 http://rbmb.net/browse.php?a_code=A-10-277-1&slc_lang=en&sid=1 Nasser Beikzadeh beiczadeh@gmail.com 100319475328460017413 100319475328460017413 Yes Khorasan Razavi Agricultural and Natural Resources Research and Education Center, AREEO, Mashhad, Iran. Abdol-Reza Varasteh varasteha@varastegan.ac.ir 100319475328460017414 100319475328460017414 No Varastegan Institute for Medical Sciences, Mashhad, Iran.