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'); Reports of Biochemistry and Molecular Biology rbmb.net Basic Sciences http://rbmb.net 1 admin 2322-3480 2322-3480 10.61882/rbmb en jalali 1392 7 1 gregorian 2013 10 1 2 1 online 1 fulltext
en Hepatitis E Virus and Serum Level Aminotransferases in Blood Donors میکروب شناسی Microbiology <p style="text-align: justify;"><em><strong>Background:</strong></em> Hepatitis E virus (HEV) infection is a self-limiting viral infection that can lead to severe complications and death. In different regions the epidemiology of this infection varies. In this study we evaluated the seroepidemiology of hepatitis E infection in Jahrom, a city in southern Iran.</p> <p style="text-align: justify;"><em><strong>Methods:</strong></em> This was a cross-sectional descriptive study of serum samples from 477 subjects, including 30 females and 447 males. HEV immunoglobulin G (IgG) and immunoglobulin M (IgM) were measured by enzyme-linked immunosorbent assays (ELISA). Alanine transaminase (ALT) and aspartate transaminase (AST) levels were also determined. Four hundred forty-seven subjects were male and 30 were female. Subjects were classified by age and sex.</p> <p style="text-align: justify;"><em><strong>Results:</strong></em> One woman (3.3%) and 25 men (5.5%) were positive for HEV antibodies (IgG and/or IgM). There was found an association between serum level of aminotransferases and seropositivity for HEV.</p> <p style="text-align: justify;"><em><strong>Conclusion:</strong></em> The result of this study indicates that HEV is an etiological factor for hepatitis in this area of IRAN. The cost benefit of active immunization in endemic regions should be evaluated because an outbreak could have tragic consequences.</p> Aminotransferase, Hepatitis E, Iran, Seroepidemiology 48 51 http://rbmb.net/browse.php?a_code=A-10-1-20&slc_lang=en&sid=1 Abdolreza Sotoodeh Jahromi 10031947532846005971 10031947532846005971 No Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran - Department of Immunology, Jahrom University of Medical Sciences, Jahrom, Iran Morteza Pourahmad Mortezapourahmad@yahoo.com 10031947532846005972 10031947532846005972 Yes Zoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, Iran - Department of Internal Medicine, Jahrom University of Medical Sciences, Jahrom, Iran