die('
Site is under construction
Dear site users
Site is under construction.
The site will be ready in less than 24 hours.
We are sorry for the inconvenience.
www.yektaweb.com
');
Reports of Biochemistry and Molecular Biology
rbmb.net
Basic Sciences
http://rbmb.net
1
admin
2322-3480
2322-3480
10.61882/rbmb
en
jalali
1393
2
1
gregorian
2014
5
1
2
2
online
1
fulltext
en
Identification and Molecular Characterization of the cDNA Encoding Cucumis melo Allergen, Cuc m 3, a Plant Pathogenesis-Related Protein
ایمنی شناسی
Immunology
<p style="text-align: justify;"><em><strong>Background:</strong></em> Melon <em>(Cucumis melo)</em> allergy is one of the most common food allergies, characterized by oral allergy syndrome. To date, two allergen molecules, Cuc m 1 and Cuc m 2, have been fully characterized in melon pulp, but there are few reports about the molecular characteristics of Cuc m 3.</p>
<p style="text-align: justify;"><strong><em>Methods:</em></strong>The Cuc m 3 cDNA has been characterized by rapid amplification of cDNA ends (RACE), which revealed a 456 base-pair (bp) fragment encoding a 151-amino acid polypeptide with a predicted molecular mass of 16.97 kDa, and identified 79 and 178 bp untranslated sequences at the 5′ and 3´ ends, respectively.</p>
<p style="text-align: justify;"><em><strong>Results:</strong></em> In silico analysis showed strong similarities between Cuc m 3 and other plant pathogen-related protein 1s from cucumber, grape, bell pepper, and tomato.</p>
<p style="text-align: justify;"><strong><em>Conclusion:</em></strong> Here we report the identification and characterization of the Cuc m 3 cDNA, which will be utilized for further analyses of structural and allergenic features of this allergen.</p>
Allergen, Cuc m 3, Melon, Plant pathogenesis-related protein 1
82
87
http://rbmb.net/browse.php?a_code=A-10-1-26&slc_lang=en&sid=1
Mojtaba
Sankian
10031947532846005991
10031947532846005991
No
Immunology Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.
Jafar
Hajavi
10031947532846005992
10031947532846005992
No
Immunology Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.
Malihe
Moghadam
10031947532846005993
10031947532846005993
No
Immunology Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.
Abdol-Reza
Varasteh
varasteha@mums.ac.ir
10031947532846005994
10031947532846005994
Yes
Allergy Research Center, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran.