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Reports of Biochemistry and Molecular Biology
rbmb.net
Basic Sciences
http://rbmb.net
1
admin
2322-3480
2322-3480
10.61882/rbmb
en
jalali
1395
2
1
gregorian
2016
5
1
4
2
online
1
fulltext
en
Sensitivity Comparison of the Skin Prick Test and Serum and Fecal Radio Allergosorbent Test (RAST) in Diagnosis of Food Allergy in Children
ایمنی شناسی
Immunology
<p style="text-align: justify;"><em><strong>Background: </strong></em>Diagnosis of food allergy is difficult in children. Food allergies are diagnosed using several methods that include medical histories, clinical examinations, skin prick and serum-specific immunoglobulin E (IgE) tests, radio-allergosorbent test (RAST), food challenge, and supervised elimination diets. In this study we evaluated allergies to cow's milk, egg, peanut, and fish in children with suspected food allergies with skin prick tests and serum and feces RAST.</p>
<p style="text-align: justify;"><em><strong>Methods:</strong></em> Forty-one children with clinical symptoms of food allergies were enrolled in the study. Skin prick tests and serum and fecal RAST were performed and compared with challenge tests.</p>
<p style="text-align: justify;"><em><strong>Results:</strong></em> The most common sites of food allergy symptoms were gastrointestinal (82.9%) and skin (48.8%). 100% of the patients responded to the challenge tests with cow’s milk, egg, peanut, and fish. 65% of the patients tested positive with the skin prick test, 12.1% tested positive with serum RAST, and 29.2% tested positive with fecal RAST.</p>
<p style="text-align: justify;"><em><strong>Conclusions:</strong></em> The skin prick test was more sensitive than serum or fecal RAST, and fecal RAST was more than twice as sensitive as serum RAST.</p>
Food Hypersensitivity, Radioallergosorbent test, Sensitivity, Specificity
98
103
http://rbmb.net/browse.php?a_code=A-10-1-56&slc_lang=en&sid=1
Hamid Reza
Kianifar
10031947532846006141
10031947532846006141
No
Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran - Clinical Research Development Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Alireza
Pourreza
10031947532846006142
10031947532846006142
No
Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Farahzad
Jabbari Azad
Jabbarif@mums.ac.ir
10031947532846006143
10031947532846006143
Yes
Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Hadis
Yousefzadeh
10031947532846006144
10031947532846006144
No
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Fatemeh
Masomi
10031947532846006145
10031947532846006145
No
Allergy Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran