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en Vitamin D Status in Osteoporotic and Diabetic Patients and Athletic Healthy Individuals from Northern Greece بیوشیمی Biochemistry مقالات اصلی Original Article <div style="text-align: justify;">Background: Vitamin D deficiency is recognised as a pandemic in the developed world. However, the importance of prudent sun exposure tends to be overlooked, which is responsible for this pandemic. Methods: We investigated the vitamin D status in 326 adults, 165 females and 161 males: 99 Osteoporosis patients, 53 Type 1 Diabetes patients, 51 Type 2 Diabetes patients, and 123 Athletic Healthy individuals, from Northern Greece, through the measurement of total calcidiol in winter and summer by immunoenzymatic assay. Results: In the Whole Sample 23.31% had severe deficiency, 13.50% mild deficiency, 17.48% insufficiency, and 45.71% adequacy at the end of winter. Mean concentrations differed significantly (p <0.001) between males and females. The prevalence of deficiency in the young was significantly lower than in the middle-aged (p = 0.004) and in the elderly (p <0.001), while it was significantly lower (p = 0.014) in the middle-aged than in the elderly. The best vitamin D status was found in the Athletic Healthy individuals, followed by the Type 1 and Type 2 Diabetic patients, while Osteoporotic patients had the poorest status. The difference in mean concentrations between winter and summer was significant (p <0.001). Conclusions: Vitamin D status deteriorated with increasing age and it was better in males than in females. Our findings suggest that outdoor physical activity in a Mediterranean country can cover the vitamin D needs of the young and the middle-aged, but not of the elderly, without the need for dietary supplements.</div> Total calcidiol, osteoporosis, Type 1 diabetes, Type 2 diabetes, Vitamin D status. 565 576 http://rbmb.net/browse.php?a_code=A-10-1048-1&slc_lang=en&sid=1 Constantine Anetakis kanetakis@bmsc.ihu.gr . 100319475328460016781 100319475328460016781 Yes Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, 57400 Sindos, Thessaloniki, Greece. Stella Mitka 100319475328460016782 100319475328460016782 No Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, 57400 Sindos, Thessaloniki, Greece. Maria Chatzidimitriou 100319475328460016783 100319475328460016783 No Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, 57400 Sindos, Thessaloniki, Greece & Bioanalysis Diagnostic Laboratory, D. Gounari 33, 54622 Thessaloniki, Greece. Konstantinos Anagnostopoulos 100319475328460016784 100319475328460016784 No Faculty of Medicine, School of Health Sciences, Democritus University of Thrace, Greece. Phaedra Eleftheriou 100319475328460016785 100319475328460016785 No Laboratory of Clinical Chemistry, Faculty of Biomedical Sciences, School of Health Sciences, Alexandrian Campus of International Hellenic University, 57400 Sindos, Thessaloniki, Greece. Theodoros Lialiaris 100319475328460016786 100319475328460016786 No Faculty of Medicine, School of Health Sciences, Democritus University of Thrace, Greece.