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Department of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Science. & Molecular and cell biology Research center, Faculty of Medicine, Mazandaran University of Medical sciences, Sari, Iran.
Abstract:   (58 Views)
Background: Staphylococcus aureus is predominant at sites of biomaterial-associated infection (BAI) and frequently infects hospitalized individuals.
Methods: The polysaccharide intercellular adhesin (PIA) and S. epidermidis rSesC protein, major macromolecules in biofilm formation, were purified under native conditions and cloned and expressed in a prokaryotic host.
Results: Purification of the macromolecules was confirmed by FTIR and Western blotting.
Conclusions: The S. epidermidis SesC protein and PIA were successfully purified. Both are considered as vaccine candidates.
Full-Text [PDF 486 kb]   (19 Downloads)    
Type of Article: Original Article | Subject: Molecular Biology
Received: 2018/08/29 | Accepted: 2018/09/9

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