Volume 11, Issue 2 (Vol.11 No.2 Jul 2022)                   rbmb.net 2022, 11(2): 209-215 | Back to browse issues page


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Mudjihartini N, Prasetya S I, Sadikin M. Plasma Protein Profile of Lactating Women from Two Primary Health Centers in Jakarta, Indonesia. rbmb.net 2022; 11 (2) :209-215
URL: http://rbmb.net/article-1-842-en.html
Department of Biochemistry, Faculty of Medicine, Universitas Indonesia.
Abstract:   (1229 Views)
Background: Plasma protein profile test is a potential laboratory method to assess nutritional status especially albumin and globulins levels which reflects protein adequacy. The purpose of this study is to evaluate plasma protein profile of lactating women from two primary health centers in Jakarta.

Methods: A cross-sectional study was conducted involving lactating women attending routine maternal examinations in two public primary health centers in Jakarta, Indonesia. The mother’s plasma total protein, albumin, globulin, and immunoglobulin levels were measured.

Results: Sixty lactating women were recruited, mostly were 28 years old, slightly overweight, bearing two children, and their recent children were 2 months old. The mean total protein level was 8.13 g/dl, albumin 5.00 g/dl, globulin 3.18 g/dl, albumin: globulin ratio 1.558, mean total IgG level of 1255.98 and mean total IgM level of 135.819. All the measured plasma protein parameters were shown to be not correlated with maternal age, maternal BMI, or maternal parity.

Discussion: The plasma total protein, albumin, globulin, as well as total IgG and IgM level of lactating women in Jakarta were within normal range. These biochemical parameters were shown to be not correlated with anthropometrical data such as maternal age and BMI. The small and relatively homogenous samples were supposed to be the cause of such findings. 

Conclusions: The plasma protein profile of lactating women in Jakarta was adequate. Further studies are required to evaluate the eligibility of plasma protein profile as biochemical parameter of nutritional status in lactating women.
Full-Text [PDF 195 kb]   (479 Downloads)    
Type of Article: Original Article | Subject: Biochemistry
Received: 2021/12/24 | Accepted: 2021/12/29 | Published: 2022/08/7

References
1. Ministry of Health, Republic of Indonesia. Basic Health Research Indonesia 2018. Available from: https://kesmas.kemkes.go.id
2. Elwakiel M, Boeren S, Hageman JA, Szeto IM, Schols HA, Hettinga KA. Variability of serum proteins in Chinese and Dutch human milk during lactation. Nutrients. 2019;11(3):499. [DOI:10.3390/nu11030499] [PMID] [PMCID]
3. Warburg O, Christian W. Isolierung und Kristallisation des Garungs ferments Enolase. Biochem Z. 1941;310:384-421.
4. Harding JR, Keyser JW. Bromocresol Green as a Reagent for Serum Albumin. Proc Assoc din Biochem. 1968;5:51-53. [DOI:10.1177/036985646800500307]
5. Mancini G, Carbonara AO, Heremans JF. Immunochemical quantitation of antigens by single radial immunodiffusion. 1965;2(3):234-254. [DOI:10.1016/0019-2791(65)90004-2]
6. Gomez-Cantarino S, Agullo-Ortuno M, Dios-Aguado M, Ugarte-Gurrutxaga M, Bouzas-Mosquera C. Prevalence of hypoproteinemia and hypoalbuminemia in pregnant women from three different socioeconomic populations. Int J Environ Res Public Health. 2020;17(17):6275. [DOI:10.3390/ijerph17176275] [PMID] [PMCID]
7. Wulandari S, Defrin, Reza M. Relationship between protein intake and serum albumin levels in first trimester chronic energydeficient pregnant women in Padang city. Science Midwifery. 2021;9(2):449-453.
8. Pervaiz Sh, Rukh G, Qayyum M. Serum protein status in women of different age and socioeconomic background and their neonates. Int J Agri Biol. 2001;3(4):394-396.
9. Adedeji AL, Adedosu OT, Afolabi OK, Badmus JA, ie LO E, Fatoki JO, et al. Serum protein profile in Nigerian women: an analysis by gestation age. Clastogenic and toxicological assessment of cashew (Anacardium occidentale) nut bark extracts in Wistar rats. 2012;4(11):38-42.
10. Das A, Teli AB, Borkotoki S. Study of liver function tests in normal pregnancy: a hospital based study. Int J Health Sci Res. 2016;6(8):156-160.
11. Ahmad HA, Muhammdsalih MM, Khidir KA. Complement protein and immunoglobulins serum levels in normal pregnant and spontaneous aborted women. Kurdistan Journal of applied research. 2018;129-133. [DOI:10.24017/science.2018.2.21]
12. Sushith S, Krishnamurthy H N, Reshma S, Janice D, Madan G, Ashok K J, et al. Serum Ischemia-Modified Albumin, Fibrinogen, High Sensitivity C- Reactive Proteins in Type-2 Diabetes Mellitus without Hypertension and Diabetes Mellitus with Hypertension: A Case-Control Study. Rep Biochem Mol Biol. 2020;9(2):241-249. [DOI:10.29252/rbmb.9.2.241] [PMID] [PMCID]
13. Jha C, Ullas Kamath S, Dash S, Prabhu Attur R, Ramachandra L, Shenoy Kallya R. Ischemia-Modified Albumin, Creatinine, and Paraoxonase-1 Levels in Serum of Patients Undergoing Intravenous Contrast-Enhanced Computed Tomography and Its Association with Contrast-Induced Nephropathy. Rep Biochem Mol Biol. 2019;8(1):72-78.

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